This is a timeline of events that occurred in 2012.
- Captain George Stacy starts a sting operation to find criminal hideouts.
- News is posted online about Dr. Curt Connors.
- Flash picks on someone and tells Peter to take a photo.
- Peter refuses and is beat up by Flash.
- Peter Parker discovers his father's papers and learns that he worked with Dr. Curt Connors.
- Pete goes to Oscorp and meets Dr. Connors.
- Peter is bitten by a radioactive spider.
- Peter begins to help Curt Connors.
- Peter picks on Flash while he play basket ball.
- Peter works late to help Curt Connors and doesn't pick up Aunt May.
- Ben Parker dies.
- Peter Parker is confronted by Flash Thompson who says he is sorry for his loss.
- Peter goes after a potential killer of Uncle Ben.
- The Angels chase him down and fight him; Peter chases Paul running away.
- Peter pursues them in his Aston Martin; He sees Mattie lying in the street and swerves to avoid her, crashing his Aston Martin.
- Paul Stacy tortures Peter Parker.
- Peter awakens in a hospital.
- Peter makes his web-shooters.
- Peter practices his new abilities.
- Peter goes after another potential killer of Uncle Ben.
- The police find out about Spider-Man.
- Peter chooses what material to wear as Spider-Man.
- Peter overhears two guys discussing about spandex.
- Peter makes his Spider-Man costume.
- Peter web-swings in his new costume.
- Peter goes after the car thief.
- Peter goes home and Aunt May finds out he has been beaten.
- Curt Connors is forced to begin human trials on the Lizard DNA.
- Mattie kissing Peter.
- Curt Connors begins human trials on himself.
- Curt Connors chases Rajit Ratha.
- Peter has dinner at Gwen's house.
- Peter saves civilians on the Brooklyn Bridge.
- An arrest warrant for Spider-Man is announced by George Stacy.
- Peter tells the origins of his abilities to Gwen Stacy.
- Peter finds out that Curt Connors is the Lizard.
- Peter goes to George Stacy to talk about Curt Connors.
- Peter goes down the sewers to track down the Lizard.
- Peter goes to Gwen's house injured.
- The Lizard attacks Peter at Midtown High; Paul Stacy attacks the Angels.
- Peter goes down into the sewers and asks Gwen to make an antidote at Oscorp.
- Peter finds out Curt Connor's plan.
- The Lizard attacks the NYPD and turns them into lizards.
- The antidote is released into the air and Curt Connors returns to human form.
- George Stacy is critically wounded, who asks him a promise to keep before dying.
- Dr. Curt Connors is taken into custody.
- George Stacy's funeral.
- Peter tells Gwen that he cannot see her anymore.
- Peter Parker meets Paul Stacy
- A trial date was set in the New York Appellate Court for alleged bio-terrorist Dr. Curt Connors.
- Dr. Rajit Ratha was identified as a badly decomposed body found in the sewers beneath lower Manhattan.
- Herman Schultz (Shocker) attempted to rob the Midtown bank but was caught by Spider-Man who webbed up the suspect.
- Herman Schultz was taken to Ravencroft Institute.
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